3r8f

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[[Image:3r8f.png|left|200px]]
 
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==Replication initiator DnaA bound to AMPPCP and single-stranded DNA==
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The line below this paragraph, containing "STRUCTURE_3r8f", creates the "Structure Box" on the page.
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<StructureSection load='3r8f' size='340' side='right'caption='[[3r8f]], [[Resolution|resolution]] 3.37&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3r8f]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. The December 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA Helicase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_12 10.2210/rcsb_pdb/mom_2013_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R8F FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.366&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3r8f| PDB=3r8f | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r8f OCA], [https://pdbe.org/3r8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r8f RCSB], [https://www.ebi.ac.uk/pdbsum/3r8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r8f ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DNAA_AQUAE DNAA_AQUAE] Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
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===Protein-DNA complex===
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==See Also==
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*[[DnaA|DnaA]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21964332 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21964332}}
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==About this Structure==
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[[3r8f]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R8F OCA].
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==Reference==
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<ref group="xtra">PMID:021964332</ref><references group="xtra"/>
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[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Berger, J M.]]
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[[Category: DNA Helicase]]
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[[Category: Chuang, K.]]
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[[Category: Large Structures]]
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[[Category: Duderstadt, K E.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Aaa+ atpase]]
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[[Category: Berger JM]]
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[[Category: Dna binding]]
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[[Category: Chuang K]]
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[[Category: Replication activator-dna complex]]
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[[Category: Duderstadt KE]]
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[[Category: Replication initiator]]
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Current revision

Replication initiator DnaA bound to AMPPCP and single-stranded DNA

PDB ID 3r8f

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