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3vpo
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant== | |
| + | <StructureSection load='3vpo' size='340' side='right'caption='[[3vpo]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3vpo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpo OCA], [https://pdbe.org/3vpo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpo RCSB], [https://www.ebi.ac.uk/pdbsum/3vpo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. | ||
| - | + | ==See Also== | |
| - | + | *[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen B]] | ||
| + | [[Category: Chen X]] | ||
| + | [[Category: Liu H]] | ||
| + | [[Category: Shao J]] | ||
| + | [[Category: Xu Z]] | ||
| + | [[Category: Yang C]] | ||
| + | [[Category: Zhang L]] | ||
| + | [[Category: Zhu L]] | ||
| + | [[Category: Zhu W]] | ||
Current revision
Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant
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Categories: Homo sapiens | Large Structures | Chen B | Chen X | Liu H | Shao J | Xu Z | Yang C | Zhang L | Zhu L | Zhu W
