4e9u

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(New page: '''Unreleased structure''' The entry 4e9u is ON HOLD Authors: Lin, F.-Y., Axelson, J., Liu, Y.-L., Zhnag, Y., Oldfield, E. Description: Thiocyante, Quinuclidine, and Diamine Inhibitors...)
Current revision (11:02, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4e9u is ON HOLD
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==Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with a thiocyanate inhibitor==
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<StructureSection load='4e9u' size='340' side='right'caption='[[4e9u]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4e9u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E9U FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RWY:2-(4-PHENOXYPHENOXY)ETHYL+THIOCYANATE'>RWY</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e9u OCA], [https://pdbe.org/4e9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e9u RCSB], [https://www.ebi.ac.uk/pdbsum/4e9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e9u ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU]
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Authors: Lin, F.-Y., Axelson, J., Liu, Y.-L., Zhnag, Y., Oldfield, E.
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==See Also==
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*[[Squalene synthase|Squalene synthase]]
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Description: Thiocyante, Quinuclidine, and Diamine Inhibitors of Squalene Synthase: Insights Into the Mechanism of Action of Head-to-Head Prenyl Transferases
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus]]
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[[Category: Axelson J]]
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[[Category: Lin F-Y]]
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[[Category: Liu Y-L]]
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[[Category: Oldfield E]]
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[[Category: Zhnag Y]]

Current revision

Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with a thiocyanate inhibitor

PDB ID 4e9u

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