4ea0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4ea0 is ON HOLD Authors: Lin, F.-Y., Liu, Y.-L., Oldfield, E. Description: Thiocyante, Quinuclidine, and Diamine Inhibitors of Squalene Synthase: I...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651== | |
| + | <StructureSection load='4ea0' size='340' side='right'caption='[[4ea0]], [[Resolution|resolution]] 2.12Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ea0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EA0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=651:(3R)-3-BIPHENYL-4-YL-1-AZABICYCLO[2.2.2]OCTAN-3-OL'>651</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ea0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea0 OCA], [https://pdbe.org/4ea0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ea0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ea0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ea0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU] | ||
| - | + | ==See Also== | |
| - | + | *[[Squalene synthase|Squalene synthase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staphylococcus aureus]] | ||
| + | [[Category: Lin F-Y]] | ||
| + | [[Category: Liu Y-L]] | ||
| + | [[Category: Oldfield E]] | ||
Current revision
Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651
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