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4ead
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine== | |
| - | + | <StructureSection load='4ead' size='340' side='right'caption='[[4ead]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ead]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0NP:2,3-DIDEOXY-2-FLUORO-3-TRIAZA-1,2-DIEN-2-IUM-1-YLURIDINE'>0NP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ead FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ead OCA], [https://pdbe.org/4ead PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ead RCSB], [https://www.ebi.ac.uk/pdbsum/4ead PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ead ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TYPH_ECOLI TYPH_ECOLI] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Abramchik YA]] | ||
| + | [[Category: Esipov RS]] | ||
| + | [[Category: Kuranova IP]] | ||
| + | [[Category: Timofeev VI]] | ||
Current revision
Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine
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