4eaq
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4eaq is ON HOLD Authors: Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Jedrzejcza, R., Joachimiak, A., Anderson, W.F., Midwest Center...) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate== | |
+ | <StructureSection load='4eaq' size='340' side='right'caption='[[4eaq]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4eaq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAQ FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eaq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eaq OCA], [https://pdbe.org/4eaq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eaq RCSB], [https://www.ebi.ac.uk/pdbsum/4eaq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eaq ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). | ||
- | + | ==See Also== | |
- | + | *[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]] | |
- | + | __TOC__ | |
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Staphylococcus aureus subsp. aureus Mu50]] | ||
+ | [[Category: Anderson WF]] | ||
+ | [[Category: Babnigg G]] | ||
+ | [[Category: Filippova EV]] | ||
+ | [[Category: Jedrzejczak R]] | ||
+ | [[Category: Joachimiak A]] | ||
+ | [[Category: Kiryukhina O]] | ||
+ | [[Category: Minasov G]] | ||
+ | [[Category: Rubin E]] | ||
+ | [[Category: Sacchettini J]] | ||
+ | [[Category: Shuvalova L]] |
Current revision
Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate
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