3r9v

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:15, 14 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3r9v.png|left|200px]]
 
-
<!--
+
==Cocrystal Structure of Proteolytically Truncated Form of IpaD from Shigella flexneri Bound to Deoxycholate==
-
The line below this paragraph, containing "STRUCTURE_3r9v", creates the "Structure Box" on the page.
+
<StructureSection load='3r9v' size='340' side='right'caption='[[3r9v]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3r9v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R9V FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
{{STRUCTURE_3r9v| PDB=3r9v | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r9v OCA], [https://pdbe.org/3r9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r9v RCSB], [https://www.ebi.ac.uk/pdbsum/3r9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r9v ProSAT]</span></td></tr>
-
 
+
</table>
-
===Cocrystal Structure of Proteolytically Truncated Form of IpaD from Shigella flexneri Bound to Deoxycholate===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/IPAD_SHIFL IPAD_SHIFL] Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.<ref>PMID:7957095</ref> <ref>PMID:15731041</ref>
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_22423359}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 22423359 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Large Structures]]
-
{{ABSTRACT_PUBMED_22423359}}
+
-
 
+
-
==About this Structure==
+
-
[[3r9v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R9V OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:022423359</ref><references group="xtra"/>
+
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
-
[[Category: Barta, M L.]]
+
[[Category: Barta ML]]
-
[[Category: Dickenson, N E.]]
+
[[Category: Dickenson NE]]
-
[[Category: Geisbrecht, B V.]]
+
[[Category: Geisbrecht BV]]
-
[[Category: Picking, W D.]]
+
[[Category: Picking WD]]
-
[[Category: Picking, W L.]]
+
[[Category: Picking WL]]
-
[[Category: Cell invasion]]
+
-
[[Category: Deoxycholate]]
+
-
[[Category: Tip protein]]
+
-
[[Category: Type iii secretion system]]
+

Current revision

Cocrystal Structure of Proteolytically Truncated Form of IpaD from Shigella flexneri Bound to Deoxycholate

PDB ID 3r9v

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3r9v"
Personal tools