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2lcs

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[[Image:2lcs.png|left|200px]]
 
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==Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p==
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The line below this paragraph, containing "STRUCTURE_2lcs", creates the "Structure Box" on the page.
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<StructureSection load='2lcs' size='340' side='right'caption='[[2lcs]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2lcs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lcs OCA], [https://pdbe.org/2lcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lcs RCSB], [https://www.ebi.ac.uk/pdbsum/2lcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lcs ProSAT]</span></td></tr>
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{{STRUCTURE_2lcs| PDB=2lcs | SCENE= }}
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</table>
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== Function ==
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===Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p===
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[https://www.uniprot.org/uniprot/NBP2_YEAST NBP2_YEAST] Negatively regulates the high-osmolarity glycerol (HOG) pathway through its negative regulation of the HOG1 kinase activity. Mediates the binding between the PTC1 phosphatase and the PBS2 MAP/ERK kinase (MEK). With PTC1, regulates endoplasmic reticulum inheritance through the cell wall integrity (CWI) MAPK pathway by modulating the MAPK, SLT2.<ref>PMID:14573466</ref> <ref>PMID:14685261</ref> <ref>PMID:16977319</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22277653 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae S288C]]
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{{ABSTRACT_PUBMED_22277653}}
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[[Category: Davidson AR]]
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[[Category: Gorelik M]]
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==About this Structure==
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[[2lcs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCS OCA].
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==Reference==
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<ref group="xtra">PMID:022277653</ref><references group="xtra"/>
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Davidson, A R.]]
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[[Category: Gorelik, M.]]
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[[Category: Adaptor]]
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[[Category: Signaling protein]]
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[[Category: Transferase]]
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Current revision

Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p

PDB ID 2lcs

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