User:Jamie Abbott/Sandbox2

== Histidyl-tRNA Synthetase ==

Histidyl tRNA Synthetase (HisRS) is a 94kD homodimer that belongs to the Class II of aminoacyl-tRNA synthetases (aaRS). Class II enzymes have a <scene name='User:Jamie_Abbott/Sandbox2/Catalytic_domain/1'>catalytic domain</scene> composed of anti-parallel β-sheets and α-helices (residues 1-325).

'''Function and Catalysis'''<StructureSection load='1KMM' size='500' side='right' caption='Structure of Histidyl-tRNA Synthetase (PDB entry [[1KMM]])' scene=''>Class II aminoacyl-tRNA synthetases aminoacylate the 3'OH of their cognate tRNAs.</StructureSection>

<scene name='User:Jamie_Abbott/Sandbox2/Hisrsdimer/2'>Dimer</scene>

<scene name='User:Jamie_Abbott/Sandbox2/Hisrsdimer_to_monomer/2'>Monomer</scene>

<scene name='User:Jamie_Abbott/Sandbox2/Motif_i/3'>Motif I</scene>

<scene name='User:Jamie_Abbott/Sandbox2/Motif_ii/2'>Motif II</scene>

<scene name='User:Jamie_Abbott/Sandbox2/Motif_iii/4'>Motif III</scene>

<scene name='User:Jamie_Abbott/Sandbox2/Hisa_loop/1'>HisA Loop</scene>

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== Mechanism ==

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== Structures ==

[http://www.pdb.org/pdb/explore/explore.do?structureId=1KMN 1KMN]

[http://www.pdb.org/pdb/explore/explore.do?structureId=1KMM 1KMM]

[http://www.pdb.org/pdb/explore/explore.do?structureId=1HTT 1HTT]

[http://www.pdb.org/pdb/explore/explore.do?structureId=2EL9 2EL9]

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== References ==

<references/>