4eiw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L)== | |
| - | + | <StructureSection load='4eiw' size='340' side='right'caption='[[4eiw]], [[Resolution|resolution]] 3.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4eiw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EIW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eiw OCA], [https://pdbe.org/4eiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eiw RCSB], [https://www.ebi.ac.uk/pdbsum/4eiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eiw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FTSH_THET8 FTSH_THET8] Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity).[HAMAP-Rule:MF_01458] Degrades preferentially unfolded substrates in a processive, ATP-dependent manner, usually after hydrophobic residues.[HAMAP-Rule:MF_01458] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermus thermophilus HB8]] | ||
| + | [[Category: Morikawa K]] | ||
| + | [[Category: Niwa H]] | ||
| + | [[Category: Suno R]] | ||
| + | [[Category: Tsuchiya D]] | ||
| + | [[Category: Yoshida M]] | ||
Current revision
Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L)
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