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3u74

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[[Image:3u74.jpg|left|200px]]
 
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==Crystal structure of stabilized human uPAR mutant==
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The line below this paragraph, containing "STRUCTURE_3u74", creates the "Structure Box" on the page.
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<StructureSection load='3u74' size='340' side='right'caption='[[3u74]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3u74]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U74 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_3u74| PDB=3u74 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u74 OCA], [https://pdbe.org/3u74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u74 RCSB], [https://www.ebi.ac.uk/pdbsum/3u74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u74 ProSAT]</span></td></tr>
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</table>
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===Crystal structure of stabilized human uPAR mutant===
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== Function ==
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[https://www.uniprot.org/uniprot/UPAR_HUMAN UPAR_HUMAN] Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_22285761}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 22285761 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22285761}}
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==About this Structure==
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[[3u74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U74 OCA].
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==Reference==
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<ref group="xtra">PMID:022285761</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Huang, M D.]]
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[[Category: Large Structures]]
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[[Category: Xu, X.]]
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[[Category: Huang MD]]
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[[Category: Yuan, C.]]
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[[Category: Xu X]]
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[[Category: Glycosylation]]
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[[Category: Yuan C]]
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[[Category: Hydrolase receptor]]
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Current revision

Crystal structure of stabilized human uPAR mutant

PDB ID 3u74

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OCA

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