3ta8

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[[Image:3ta8.png|left|200px]]
 
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==Crystal structure HP-NAP from strain YS39 iron loaded (cocrystallization 5mM)==
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The line below this paragraph, containing "STRUCTURE_3ta8", creates the "Structure Box" on the page.
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<StructureSection load='3ta8' size='340' side='right'caption='[[3ta8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ta8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TA8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TA8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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{{STRUCTURE_3ta8| PDB=3ta8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ta8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ta8 OCA], [https://pdbe.org/3ta8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ta8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ta8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ta8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/G1UIZ3_HELPX G1UIZ3_HELPX]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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A new crystal lattice structure of Helicobacter pylori neutrophil-activating protein (HP-NAP) has been determined in two forms: the native state (Apo) at 2.20 A resolution and an iron-loaded form (Fe-load) at 2.50 A resolution. The highly solvated packing of the dodecameric shell is suitable for crystallographic study of the metal ion-uptake pathway. Like other bacterioferritins, HP-NAP forms a spherical dodecamer with 23 symmetry including two kinds of channels. Iron loading causes a series of conformational changes of amino-acid residues (Trp26, Asp52 and Glu56) at the ferroxidase centre.
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===Crystal structure HP-NAP from strain YS39 iron loaded (cocrystallization 5mM)===
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A new crystal lattice structure of Helicobacter pylori neutrophil-activating protein (HP-NAP).,Tsuruta O, Yokoyama H, Fujii S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):134-40., Epub 2012 Jan 25. PMID:22297984<ref>PMID:22297984</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_22297984}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3ta8" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 22297984 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_22297984}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[3ta8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TA8 OCA].
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==Reference==
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<ref group="xtra">PMID:022297984</ref><references group="xtra"/>
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[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Fujii, S.]]
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[[Category: Large Structures]]
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[[Category: Tsuruta, O.]]
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[[Category: Fujii S]]
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[[Category: Yokoyama, H.]]
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[[Category: Tsuruta O]]
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[[Category: Dodecamer]]
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[[Category: Yokoyama H]]
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[[Category: Four-helix bundle]]
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[[Category: Metal transport]]
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Current revision

Crystal structure HP-NAP from strain YS39 iron loaded (cocrystallization 5mM)

PDB ID 3ta8

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