4e1b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:46, 6 November 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4e1b.png|left|200px]]
 
-
<!--
+
==Re-refinement of PDB entry 2EQA - SUA5 protein from Sulfolobus tokodaii with bound threonylcarbamoyladenylate==
-
The line below this paragraph, containing "STRUCTURE_4e1b", creates the "Structure Box" on the page.
+
<StructureSection load='4e1b' size='340' side='right'caption='[[4e1b]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[4e1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E1B FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=TXA:THREONYLCARBAMOYLADENYLATE'>TXA</scene></td></tr>
-
{{STRUCTURE_4e1b| PDB=4e1b | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e1b OCA], [https://pdbe.org/4e1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e1b RCSB], [https://www.ebi.ac.uk/pdbsum/4e1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e1b ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SUA5_SULTO SUA5_SULTO] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). Probably catalyzes the conversion of L-threonine, bicarbonate/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of pyrophosphate. Shows ATP hydrolysis activity in vitro, producing AMP.<ref>PMID:22383337</ref>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
An ancient reaction vessel: TobZ carbamoylates the antibiotic tobramycin to form nebramycin 5'. The YrdC-like domain (blue) catalyzes the formation of the novel intermediate carbamoyladenylate, which is channeled through a common "reaction chamber" to the Kae1-like domain (brown), site of carbamoyl transfer.
-
===Re-refinement of PDB entry 2EQA - SUA5 protein from Sulfolobus tokodaii with bound threonylcarbamoyladenylate===
+
The O-Carbamoyltransferase TobZ Catalyzes an Ancient Enzymatic Reaction.,Parthier C, Gorlich S, Jaenecke F, Breithaupt C, Brauer U, Fandrich U, Clausnitzer D, Wehmeier UF, Bottcher C, Scheel D, Stubbs MT Angew Chem Int Ed Engl. 2012 Mar 1. doi: 10.1002/anie.201108896. PMID:22383337<ref>PMID:22383337</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
==About this Structure==
+
</div>
-
[[4e1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E1B OCA].
+
<div class="pdbe-citations 4e1b" style="background-color:#fffaf0;"></div>
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:018004774</ref><ref group="xtra">PMID:022383337</ref><references group="xtra"/>
+
__TOC__
-
[[Category: Sulfolobus tokodaii]]
+
</StructureSection>
-
[[Category: Boettcher, C.]]
+
[[Category: Large Structures]]
-
[[Category: Braeuer, U.]]
+
[[Category: Sulfurisphaera tokodaii str. 7]]
-
[[Category: Breithaupt, C.]]
+
[[Category: Boettcher C]]
-
[[Category: Clausnitzer, D.]]
+
[[Category: Braeuer U]]
-
[[Category: Fandrich, U.]]
+
[[Category: Breithaupt C]]
-
[[Category: Goerlich, S.]]
+
[[Category: Clausnitzer D]]
-
[[Category: Jaenecke, F.]]
+
[[Category: Fandrich U]]
-
[[Category: Parthier, C.]]
+
[[Category: Goerlich S]]
-
[[Category: Scheel, D.]]
+
[[Category: Jaenecke F]]
-
[[Category: Stubbs, M T.]]
+
[[Category: Parthier C]]
-
[[Category: Wehmeier, U F.]]
+
[[Category: Scheel D]]
-
[[Category: Rna binding protein]]
+
[[Category: Stubbs MT]]
-
[[Category: Sua5 domain]]
+
[[Category: Wehmeier UF]]
-
[[Category: Trna modification t6a]]
+
-
[[Category: Yrdc domain]]
+
-
[[Category: Yrdc/ribb fold]]
+

Current revision

Re-refinement of PDB entry 2EQA - SUA5 protein from Sulfolobus tokodaii with bound threonylcarbamoyladenylate

PDB ID 4e1b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4e1b"
Personal tools