3uvv

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[[Image:3uvv.png|left|200px]]
 
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==Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid==
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The line below this paragraph, containing "STRUCTURE_3uvv", creates the "Structure Box" on the page.
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<StructureSection load='3uvv' size='340' side='right'caption='[[3uvv]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3uvv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UVV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9CR:(9CIS)-RETINOIC+ACID'>9CR</scene>, <scene name='pdbligand=T3:3,5,3TRIIODOTHYRONINE'>T3</scene></td></tr>
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{{STRUCTURE_3uvv| PDB=3uvv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uvv OCA], [https://pdbe.org/3uvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uvv RCSB], [https://www.ebi.ac.uk/pdbsum/3uvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uvv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/THA_CHICK THA_CHICK] Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
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===Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid===
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==See Also==
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*[[Retinoid X receptor 3D structures|Retinoid X receptor 3D structures]]
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*[[Thyroid hormone receptor 3D structures|Thyroid hormone receptor 3D structures]]
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22474364 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22474364}}
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==About this Structure==
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[[3uvv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVV OCA].
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==Reference==
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<ref group="xtra">PMID:022474364</ref><references group="xtra"/>
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Brunzelle, J S.]]
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[[Category: Large Structures]]
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[[Category: Fernandez, E J.]]
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[[Category: Brunzelle JS]]
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[[Category: Putcha, B D.K.]]
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[[Category: Fernandez EJ]]
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[[Category: Wright, E.]]
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[[Category: Putcha B-DK]]
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[[Category: Allostery]]
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[[Category: Wright E]]
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[[Category: Alpha helical sandwich]]
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[[Category: Hormone receptor-hormone receptor complex]]
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[[Category: Tr-rxr heterodimer]]
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[[Category: Transactivation]]
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Current revision

Crystal Structure of the ligand binding domains of the thyroid receptor:retinoid X receptor complexed with 3,3',5 triiodo-L-thyronine and 9-cis retinoic acid

PDB ID 3uvv

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