3hje
From Proteopedia
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| - | [[Image:3hje.png|left|200px]] | ||
| - | < | + | ==Crystal structure of sulfolobus tokodaii hypothetical maltooligosyl trehalose synthase== |
| - | + | <StructureSection load='3hje' size='340' side='right'caption='[[3hje]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | You may | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[3hje]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HJE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hje OCA], [https://pdbe.org/3hje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hje RCSB], [https://www.ebi.ac.uk/pdbsum/3hje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hje ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q973H2_SULTO Q973H2_SULTO] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/3hje_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hje ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The Sulfolobus tokodaii protein ST0929 shares close structural homology with S. acidocaldarius maltooligosyl trehalose synthase (SaMTSase), suggesting that the two enzymes share a common enzymatic mechanism. MTSase is one of a pair of enzymes that catalyze trehalose biosynthesis. The relative geometries of the ST0929 and SaMTSase active sites were found to be essentially identical. ST0929 also includes the unique tyrosine cluster that encloses the reducing-end glucose subunit in Sulfolobus sp. MTSases. The current structure provides insight into the structural basis of the increase in the hydrolase side reaction that is observed for mutants in which a phenylalanine residue is replaced by a tyrosine residue in the subsite +1 tyrosine cluster of Sulfolobus sp. | ||
| - | + | Structure of ST0929, a putative glycosyl transferase from Sulfolobus tokodaii.,Cielo CB, Okazaki S, Suzuki A, Mizushima T, Masui R, Kuramitsu S, Yamane T Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1;66(Pt 4):397-400., Epub 2010 Mar 26. PMID:20383007<ref>PMID:20383007</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 3hje" style="background-color:#fffaf0;"></div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | == | + | [[Category: Large Structures]] |
| - | + | [[Category: Sulfurisphaera tokodaii str. 7]] | |
| - | + | [[Category: Cielo CBC]] | |
| - | == | + | [[Category: Kuramitsu S]] |
| - | < | + | [[Category: Masui R]] |
| - | [[Category: | + | [[Category: Mizushima T]] |
| - | [[Category: Cielo | + | [[Category: Okazaki S]] |
| - | [[Category: Kuramitsu | + | [[Category: Suzuki A]] |
| - | [[Category: Masui | + | [[Category: Yamane T]] |
| - | [[Category: Mizushima | + | |
| - | [[Category: Okazaki | + | |
| - | [[Category: Suzuki | + | |
| - | [[Category: Yamane | + | |
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Current revision
Crystal structure of sulfolobus tokodaii hypothetical maltooligosyl trehalose synthase
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