4ee2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution== | |
| - | + | <StructureSection load='4ee2' size='340' side='right'caption='[[4ee2]], [[Resolution|resolution]] 1.91Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ee2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EE2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ee2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ee2 OCA], [https://pdbe.org/4ee2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ee2 RCSB], [https://www.ebi.ac.uk/pdbsum/4ee2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ee2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus anthracis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kintzer AF]] | ||
| + | [[Category: Krantz BA]] | ||
Current revision
Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution
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