4ewa
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4ewa is ON HOLD Authors: Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W., Liu, A Description: Study on structure and function relation...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Study on structure and function relationships in human Pirin with Fe ion== | |
| + | <StructureSection load='4ewa' size='340' side='right'caption='[[4ewa]], [[Resolution|resolution]] 2.47Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ewa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EWA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.47Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewa OCA], [https://pdbe.org/4ewa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ewa RCSB], [https://www.ebi.ac.uk/pdbsum/4ewa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ewa ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PIR_HUMAN PIR_HUMAN] Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has quercetin 2,3-dioxygenase activity (in vitro).<ref>PMID:9079676</ref> <ref>PMID:17288615</ref> <ref>PMID:20010624</ref> <ref>PMID:20711196</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Dioxygenase 3D structures|Dioxygenase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen L]] | ||
| + | [[Category: Fu R]] | ||
| + | [[Category: Liu A]] | ||
| + | [[Category: Liu F]] | ||
| + | [[Category: Rehmani I]] | ||
| + | [[Category: Serrano V]] | ||
| + | [[Category: Wilson DW]] | ||
Current revision
Study on structure and function relationships in human Pirin with Fe ion
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Categories: Homo sapiens | Large Structures | Chen L | Fu R | Liu A | Liu F | Rehmani I | Serrano V | Wilson DW
