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1p1x

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[[Image:1p1x.png|left|200px]]
 
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==Comparison of class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase determined at 0.99 Angstrom resolution==
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The line below this paragraph, containing "STRUCTURE_1p1x", creates the "Structure Box" on the page.
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<StructureSection load='1p1x' size='340' side='right'caption='[[1p1x]], [[Resolution|resolution]] 0.99&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p1x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P1X FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.99&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1x OCA], [https://pdbe.org/1p1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p1x RCSB], [https://www.ebi.ac.uk/pdbsum/1p1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p1x ProSAT]</span></td></tr>
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{{STRUCTURE_1p1x| PDB=1p1x | SCENE= }}
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</table>
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== Function ==
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===Comparison of class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase determined at 0.99 Angstrom resolution===
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[https://www.uniprot.org/uniprot/DEOC_ECOLI DEOC_ECOLI] Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.[HAMAP-Rule:MF_00592]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15476818}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15476818 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p1/1p1x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15476818}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p1x ConSurf].
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[[1p1x]] is a 2 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1X OCA].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aldolase|Aldolase]]
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*[[Aldolase 3D structures|Aldolase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015476818</ref><references group="xtra"/>
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[[Category: Escherichia coli K-12]]
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[[Category: Deoxyribose-phosphate aldolase]]
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[[Category: Large Structures]]
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[[Category: Escherichia coli k-12]]
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[[Category: Heine A]]
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[[Category: Heine, A.]]
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[[Category: Luz JG]]
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[[Category: Luz, J G.]]
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[[Category: Wilson IA]]
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[[Category: Wilson, I A.]]
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[[Category: Wong CH]]
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[[Category: Wong, C H.]]
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[[Category: Alpha-beta barrel]]
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[[Category: Lyase]]
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[[Category: Tim barrel]]
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Current revision

Comparison of class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase determined at 0.99 Angstrom resolution

PDB ID 1p1x

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