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4e52
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D== | |
| - | + | <StructureSection load='4e52' size='340' side='right'caption='[[4e52]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4e52]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E52 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GMH:L-GLYCERO-D-MANNO-HEPTOPYRANOSE'>GMH</scene>, <scene name='pdbligand=KD5:4,7-ANHYDRO-3-DEOXY-D-MANNO-OCT-2-ULOSONIC+ACID'>KD5</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e52 OCA], [https://pdbe.org/4e52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e52 RCSB], [https://www.ebi.ac.uk/pdbsum/4e52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e52 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Greenhough TJ]] | ||
| + | [[Category: Shrive AK]] | ||
Current revision
Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D
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