4eza
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4eza is ON HOLD Authors: Van Aalten, D.M., Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C...) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2== | |
- | + | <StructureSection load='4eza' size='340' side='right'caption='[[4eza]], [[Resolution|resolution]] 1.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4eza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZA FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eza OCA], [https://pdbe.org/4eza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eza RCSB], [https://www.ebi.ac.uk/pdbsum/4eza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eza ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Agacan M]] | ||
+ | [[Category: Arrowsmith CH]] | ||
+ | [[Category: Batty IH]] | ||
+ | [[Category: Bochkarev A]] | ||
+ | [[Category: Bountra C]] | ||
+ | [[Category: Crombet L]] | ||
+ | [[Category: Dixon MJ]] | ||
+ | [[Category: Downes CP]] | ||
+ | [[Category: Edwards AM]] | ||
+ | [[Category: Gray A]] | ||
+ | [[Category: Leslie NR]] | ||
+ | [[Category: Nedyalkova L]] | ||
+ | [[Category: Park H]] | ||
+ | [[Category: Schenning M]] | ||
+ | [[Category: Tempel W]] | ||
+ | [[Category: Tong Y]] | ||
+ | [[Category: Van Aalten DMF]] | ||
+ | [[Category: Weigelt J]] | ||
+ | [[Category: Zhong N]] |
Current revision
Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2
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Categories: Homo sapiens | Large Structures | Agacan M | Arrowsmith CH | Batty IH | Bochkarev A | Bountra C | Crombet L | Dixon MJ | Downes CP | Edwards AM | Gray A | Leslie NR | Nedyalkova L | Park H | Schenning M | Tempel W | Tong Y | Van Aalten DMF | Weigelt J | Zhong N