4eza

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(New page: '''Unreleased structure''' The entry 4eza is ON HOLD Authors: Van Aalten, D.M., Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C...)
Current revision (11:07, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4eza is ON HOLD
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==Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2==
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<StructureSection load='4eza' size='340' side='right'caption='[[4eza]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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Authors: Van Aalten, D.M., Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4eza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZA FirstGlance]. <br>
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Description: Crystal structure of the GAP-related domain of IQGAP2
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eza OCA], [https://pdbe.org/4eza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eza RCSB], [https://www.ebi.ac.uk/pdbsum/4eza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eza ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IQGA2_HUMAN IQGA2_HUMAN] Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Agacan M]]
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[[Category: Arrowsmith CH]]
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[[Category: Batty IH]]
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[[Category: Bochkarev A]]
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[[Category: Bountra C]]
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[[Category: Crombet L]]
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[[Category: Dixon MJ]]
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[[Category: Downes CP]]
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[[Category: Edwards AM]]
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[[Category: Gray A]]
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[[Category: Leslie NR]]
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[[Category: Nedyalkova L]]
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[[Category: Park H]]
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[[Category: Schenning M]]
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[[Category: Tempel W]]
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[[Category: Tong Y]]
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[[Category: Van Aalten DMF]]
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[[Category: Weigelt J]]
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[[Category: Zhong N]]

Current revision

Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2

PDB ID 4eza

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