4ea0

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[[Image:4ea0.png|left|200px]]
 
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==Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651==
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The line below this paragraph, containing "STRUCTURE_4ea0", creates the "Structure Box" on the page.
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<StructureSection load='4ea0' size='340' side='right'caption='[[4ea0]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4ea0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EA0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=651:(3R)-3-BIPHENYL-4-YL-1-AZABICYCLO[2.2.2]OCTAN-3-OL'>651</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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{{STRUCTURE_4ea0| PDB=4ea0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ea0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ea0 OCA], [https://pdbe.org/4ea0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ea0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ea0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ea0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CRTM_STAAU CRTM_STAAU]
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===Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651===
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==See Also==
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*[[Squalene synthase|Squalene synthase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22486710 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22486710}}
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==About this Structure==
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[[4ea0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EA0 OCA].
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==Reference==
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<ref group="xtra">PMID:022486710</ref><references group="xtra"/>
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[[Category: 4,4'-diapophytoene synthase]]
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[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Lin, F Y.]]
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[[Category: Lin F-Y]]
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[[Category: Liu, Y L.]]
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[[Category: Liu Y-L]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Quinuclidine inhibitor]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651

PDB ID 4ea0

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