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4at7
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4at7 is ON HOLD Authors: Wolkowicz, U.M., Cook, A.G. Description: Crystal structure of the NF90-NF45 dimerisation domain complex) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the NF90-NF45 dimerisation domain complex== | |
| - | + | <StructureSection load='4at7' size='340' side='right'caption='[[4at7]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4at7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AT7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.902Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4at7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4at7 OCA], [https://pdbe.org/4at7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4at7 RCSB], [https://www.ebi.ac.uk/pdbsum/4at7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4at7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ILF2_MOUSE ILF2_MOUSE] Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA (By similarity).<ref>PMID:10574923</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Cook AG]] | ||
| + | [[Category: Wolkowicz UM]] | ||
Current revision
Crystal structure of the NF90-NF45 dimerisation domain complex
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