4erc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of VHZ bound to metavanadate== | |
| + | <StructureSection load='4erc' size='340' side='right'caption='[[4erc]], [[Resolution|resolution]] 1.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4erc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ERC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ERC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VN4:OXIDO(DIOXO)VANADIUM'>VN4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4erc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4erc OCA], [https://pdbe.org/4erc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4erc RCSB], [https://www.ebi.ac.uk/pdbsum/4erc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4erc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DUS23_HUMAN DUS23_HUMAN] Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).<ref>PMID:15201283</ref> <ref>PMID:15147733</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Alvan CH]] | ||
| + | [[Category: Sean JJ]] | ||
| + | [[Category: Vyacheslav K]] | ||
Current revision
Structure of VHZ bound to metavanadate
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