4ewp

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'''Unreleased structure'''
 
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The entry 4ewp is ON HOLD until Paper Publication
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==Crystal structure of FabH from Micrococcus luteus==
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<StructureSection load='4ewp' size='340' side='right'caption='[[4ewp]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ewp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Micrococcus_luteus_NCTC_2665 Micrococcus luteus NCTC 2665]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EWP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.198&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ewp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewp OCA], [https://pdbe.org/4ewp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ewp RCSB], [https://www.ebi.ac.uk/pdbsum/4ewp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ewp ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C5CAR9_MICLC C5CAR9_MICLC] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids (By similarity).[HAMAP-Rule:MF_01815]
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Authors: Pereira, J.H., Goh, E.-B., Keasling, J.D., Beller, H.R., Adams, P.D.
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==See Also==
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*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
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Description: Crystal structure of FabH from Micrococcus luteus
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Micrococcus luteus NCTC 2665]]
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[[Category: Adams PD]]
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[[Category: Beller HR]]
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[[Category: Goh E-B]]
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[[Category: Keasling JD]]
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[[Category: Pereira JH]]

Current revision

Crystal structure of FabH from Micrococcus luteus

PDB ID 4ewp

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