3s1g

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[[Image:3s1g.jpg|left|200px]]
 
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==tRNA-Guanine Transglycosylase in complex with lin-Benzohypoxanthine Inhibitor==
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The line below this paragraph, containing "STRUCTURE_3s1g", creates the "Structure Box" on the page.
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<StructureSection load='3s1g' size='340' side='right'caption='[[3s1g]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S1G FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ITE:2-(METHYLAMINO)-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE'>ITE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3s1g| PDB=3s1g | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s1g OCA], [https://pdbe.org/3s1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s1g RCSB], [https://www.ebi.ac.uk/pdbsum/3s1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s1g ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
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===tRNA-Guanine Transglycosylase in complex with lin-Benzohypoxanthine Inhibitor===
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==See Also==
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*[[TRNA-guanine transglycosylase 3D structures|TRNA-guanine transglycosylase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3s1g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S1G OCA].
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[[Category: Large Structures]]
[[Category: Zymomonas mobilis]]
[[Category: Zymomonas mobilis]]
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[[Category: TRNA-guanine transglycosylase]]
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[[Category: Heine A]]
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[[Category: Heine, A.]]
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[[Category: Immekus F]]
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[[Category: Immekus, F.]]
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[[Category: Klebe G]]
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[[Category: Klebe, G.]]
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[[Category: Biosynthesis]]
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[[Category: Glycosyltransferase]]
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[[Category: Metal-binding]]
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[[Category: Queuosine]]
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[[Category: Tim barrel]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Trna]]
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[[Category: Trna processing]]
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Current revision

tRNA-Guanine Transglycosylase in complex with lin-Benzohypoxanthine Inhibitor

PDB ID 3s1g

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