4dxa

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[[Image:4dxa.png|left|200px]]
 
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==Co-crystal structure of Rap1 in complex with KRIT1==
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The line below this paragraph, containing "STRUCTURE_4dxa", creates the "Structure Box" on the page.
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<StructureSection load='4dxa' size='340' side='right'caption='[[4dxa]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4dxa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DXA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_4dxa| PDB=4dxa | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dxa OCA], [https://pdbe.org/4dxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dxa RCSB], [https://www.ebi.ac.uk/pdbsum/4dxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dxa ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAP1B_HUMAN RAP1B_HUMAN] GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction.<ref>PMID:20332120</ref> <ref>PMID:18660803</ref>
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===Co-crystal structure of Rap1 in complex with KRIT1===
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==See Also==
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22577140 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22577140}}
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==About this Structure==
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[[4dxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXA OCA].
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==Reference==
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<ref group="xtra">PMID:022577140</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Small monomeric GTPase]]
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[[Category: Large Structures]]
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[[Category: Boggon, T J.]]
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[[Category: Boggon TJ]]
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[[Category: Li, X.]]
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[[Category: Li X]]
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[[Category: Zhang, R.]]
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[[Category: Zhang R]]
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[[Category: Cytoplasmic]]
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[[Category: Ferm]]
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[[Category: Gtp binding]]
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[[Category: Gtpase]]
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[[Category: Protein binding]]
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[[Category: Protein-protein interaction]]
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Current revision

Co-crystal structure of Rap1 in complex with KRIT1

PDB ID 4dxa

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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