3ssc

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[[Image:3ssc.jpg|left|200px]]
 
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==DNA binding domain of restriction endonuclease bound to DNA==
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The line below this paragraph, containing "STRUCTURE_3ssc", creates the "Structure Box" on the page.
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<StructureSection load='3ssc' size='340' side='right'caption='[[3ssc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ssc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
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{{STRUCTURE_3ssc| PDB=3ssc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssc OCA], [https://pdbe.org/3ssc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssc RCSB], [https://www.ebi.ac.uk/pdbsum/3ssc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssc ProSAT]</span></td></tr>
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</table>
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===DNA binding domain of restriction endonuclease bound to DNA===
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== Function ==
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[https://www.uniprot.org/uniprot/MCRB_ECOLI MCRB_ECOLI] Recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad range of DNA methylases and appears to act against 5-methylcytosine preceded by a purine residue. Binds to DNA containing methylated cytosines; also binds to GTP. Isoform 33 kDa is less active than isoform 51 kDa and may play a role in regulating the activity of isoform 51 kDa by competing with it in DNA and protein binding abilities.
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_22570415}}, adds the Publication Abstract to the page
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[[Category: Escherichia coli K-12]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22570415 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Grazulis S]]
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{{ABSTRACT_PUBMED_22570415}}
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[[Category: Siksnys V]]
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[[Category: Sukackaite R]]
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==About this Structure==
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[[3ssc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSC OCA].
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==Reference==
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<ref group="xtra">PMID:022570415</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
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[[Category: Grazulis, S.]]
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[[Category: Siksnys, V.]]
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[[Category: Sukackaite, R.]]
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[[Category: 5-methylcytosine]]
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[[Category: Base flipping complex]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Protein-dna complex]]
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[[Category: Restriction endonuclease]]
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Current revision

DNA binding domain of restriction endonuclease bound to DNA

PDB ID 3ssc

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OCA

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