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3ror

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[[Image:3ror.jpg|left|200px]]
 
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==Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase==
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The line below this paragraph, containing "STRUCTURE_3ror", creates the "Structure Box" on the page.
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<StructureSection load='3ror' size='340' side='right'caption='[[3ror]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ror]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ROR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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{{STRUCTURE_3ror| PDB=3ror | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ror FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ror OCA], [https://pdbe.org/3ror PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ror RCSB], [https://www.ebi.ac.uk/pdbsum/3ror PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ror ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MAP12_MYCTU MAP12_MYCTU] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[HAMAP-Rule:MF_01974]<ref>PMID:19688379</ref> <ref>PMID:20038112</ref>
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===Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase===
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[3ror]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROR OCA].
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__TOC__
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[[Category: Methionyl aminopeptidase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Addlagatta, A.]]
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[[Category: Addlagatta A]]
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[[Category: Kishor, C.]]
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[[Category: Kishor C]]
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[[Category: Reddi, R.]]
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[[Category: Reddi R]]
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[[Category: Hydrolase]]
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[[Category: Methionine excision]]
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[[Category: Pitabread fold]]
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Current revision

Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase

PDB ID 3ror

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