4asx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:34, 20 December 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4asx.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dihydro-Bauerine C==
-
The line below this paragraph, containing "STRUCTURE_4asx", creates the "Structure Box" on the page.
+
<StructureSection load='4asx' size='340' side='right'caption='[[4asx]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[4asx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ASX FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6OJ:7,8-BIS(CHLORANYL)-9-METHYL-3,4-DIHYDRO-2H-PYRIDO[3,4-B]INDOL-1-ONE'>6OJ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
{{STRUCTURE_4asx| PDB=4asx | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4asx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4asx OCA], [https://pdbe.org/4asx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4asx RCSB], [https://www.ebi.ac.uk/pdbsum/4asx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4asx ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with a beta-carboline inhibitor===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/AVR2A_HUMAN AVR2A_HUMAN] On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[4asx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ASX OCA].
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Receptor protein serine/threonine kinase]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Beltrami, A.]]
+
[[Category: Beltrami A]]
-
[[Category: Bountra, C.]]
+
[[Category: Bountra C]]
-
[[Category: Bracher, F.]]
+
[[Category: Bracher F]]
-
[[Category: Bullock, A.]]
+
[[Category: Bullock A]]
-
[[Category: Canning, P.]]
+
[[Category: Canning P]]
-
[[Category: Chaikuad, A.]]
+
[[Category: Chaikuad A]]
-
[[Category: Cooper, C D.O.]]
+
[[Category: Cooper CDO]]
-
[[Category: Delfit, F Von.]]
+
[[Category: Edwards AM]]
-
[[Category: Edwards, A M.]]
+
[[Category: Kochan G]]
-
[[Category: Kochan, G.]]
+
[[Category: Krojer T]]
-
[[Category: Krojer, T.]]
+
[[Category: Mahajan P]]
-
[[Category: Mahajan, P.]]
+
[[Category: Pohl B]]
-
[[Category: Pohl, B.]]
+
[[Category: Williams E]]
-
[[Category: Williams, E.]]
+
[[Category: Von Delft F]]
-
[[Category: Protein kinase]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dihydro-Bauerine C

PDB ID 4asx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4asx"
Personal tools