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3uu8

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[[Image:3uu8.png|left|200px]]
 
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==The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' mutant reduced in solution==
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The line below this paragraph, containing "STRUCTURE_3uu8", creates the "Structure Box" on the page.
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<StructureSection load='3uu8' size='340' side='right'caption='[[3uu8]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3uu8]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus Gloeobacter violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UU8 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr>
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{{STRUCTURE_3uu8| PDB=3uu8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uu8 OCA], [https://pdbe.org/3uu8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uu8 RCSB], [https://www.ebi.ac.uk/pdbsum/3uu8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uu8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
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===The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' mutant reduced in solution===
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22580559 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_22580559}}
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==About this Structure==
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[[3uu8]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Gloeobacter_violaceus Gloeobacter violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UU8 OCA].
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==Reference==
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<ref group="xtra">PMID:022580559</ref><references group="xtra"/>
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[[Category: Gloeobacter violaceus]]
[[Category: Gloeobacter violaceus]]
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[[Category: Corringer, P J.]]
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[[Category: Large Structures]]
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[[Category: Delarue, M.]]
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[[Category: Corringer PJ]]
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[[Category: Nury, H.]]
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[[Category: Delarue M]]
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[[Category: Sauguet, L.]]
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[[Category: Nury H]]
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[[Category: Cys-loop receptor family]]
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[[Category: Sauguet L]]
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[[Category: Membrane protein]]
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[[Category: Transport protein]]
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Current revision

The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' mutant reduced in solution

PDB ID 3uu8

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