3v3t

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[[Image:3v3t.png|left|200px]]
 
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==Crystal structure of Clostridium botulinum phage c-st TubZ==
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The line below this paragraph, containing "STRUCTURE_3v3t", creates the "Structure Box" on the page.
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<StructureSection load='3v3t' size='340' side='right'caption='[[3v3t]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3v3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum_C_str._Stockholm Clostridium botulinum C str. Stockholm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V3T FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.302&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v3t OCA], [https://pdbe.org/3v3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v3t RCSB], [https://www.ebi.ac.uk/pdbsum/3v3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v3t ProSAT]</span></td></tr>
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{{STRUCTURE_3v3t| PDB=3v3t | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TUBZ_CBCP TUBZ_CBCP] A tubulin-like, filament forming GTPase; the motor component of the type III partition system presumably used to ensure correct segregation of this bacteriophage. In the presence of Mg(2+) and GTP (or GTP-gamma-S) assembles into filaments which upon polymerization are almost exclusively bound to GDP. Filament formation is cooperative, requiring a critical concentration. Formation occurs very quickly and is followed by disassembly as GTP is consumed. Unlike its plasmid homolog in B.thuringiensis (AC Q8KNP3) GTP-gamma-S does not alter filament formation (PubMed:22538818, PubMed:28230082). When forced to assemble with GDP instead of GTP it makes much stiffer, thicker filaments (PubMed:28230082). The filaments bind a DNA centromere-like site (tubC)-TubR complex which extends to surround the TubZ filaments (PubMed:22538818). Highly dynamic filaments grow at the plus end and depolymerize at the minus end, a process called treadmilling. TubR-tubC complexes track the depolymerizing minus end of the filament, probably pulling phage DNA within the cell (By similarity).[UniProtKB:Q8KNP3]<ref>PMID:22538818</ref> <ref>PMID:28230082</ref>
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===Crystal structure of Clostridium botulinum phage c-st TubZ===
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==See Also==
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*[[Cell division protein 3D structures|Cell division protein 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 22538818 is the PubMed ID number.
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[[Category: Clostridium botulinum C str. Stockholm]]
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{{ABSTRACT_PUBMED_22538818}}
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[[Category: Large Structures]]
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[[Category: Oliva MA]]
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==About this Structure==
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[[3v3t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_botulinum_c Clostridium botulinum c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V3T OCA].
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==Reference==
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<ref group="xtra">PMID:022538818</ref><references group="xtra"/>
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[[Category: Clostridium botulinum c]]
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[[Category: Oliva, M A.]]
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[[Category: Gtp binding]]
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[[Category: Gtpase]]
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[[Category: Rossmann fold]]
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[[Category: Structural protein]]
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[[Category: Tubulin/ftsz related]]
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[[Category: Tubz]]
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Current revision

Crystal structure of Clostridium botulinum phage c-st TubZ

PDB ID 3v3t

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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