4fbw

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(New page: '''Unreleased structure''' The entry 4fbw is ON HOLD Authors: Schiller, C.B., Lammens, K., Hopfner, K.P. Description: Crystal structure of an unfused Mre11-Nbs1 complex with two mangan...)
Current revision (11:13, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4fbw is ON HOLD
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==Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site==
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<StructureSection load='4fbw' size='340' side='right'caption='[[4fbw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Schiller, C.B., Lammens, K., Hopfner, K.P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4fbw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FBW FirstGlance]. <br>
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Description: Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fbw OCA], [https://pdbe.org/4fbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fbw RCSB], [https://www.ebi.ac.uk/pdbsum/4fbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fbw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAD32_SCHPO RAD32_SCHPO] Required for the repair of double strand breaks (DSB) caused by gamma and UV radiation. May work in conjunction with rhp51.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Hopfner KP]]
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[[Category: Lammens K]]
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[[Category: Schiller CB]]

Current revision

Crystal structure of an unfused Mre11-Nbs1 complex with two manganese ions per active site

PDB ID 4fbw

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