4elz

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[[Image:4elz.jpg|left|200px]]
 
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==CCDBVFI:GYRA14VFI==
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The line below this paragraph, containing "STRUCTURE_4elz", creates the "Structure Box" on the page.
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<StructureSection load='4elz' size='340' side='right'caption='[[4elz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4elz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_fischeri_ES114 Aliivibrio fischeri ES114] and [https://en.wikipedia.org/wiki/Aliivibrio_fischeri_MJ11 Aliivibrio fischeri MJ11]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kua 3kua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ELZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_4elz| PDB=4elz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4elz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4elz OCA], [https://pdbe.org/4elz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4elz RCSB], [https://www.ebi.ac.uk/pdbsum/4elz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4elz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5E5J7_ALIF1 Q5E5J7_ALIF1] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01897]
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===CCDBVFI:GYRA14VFI===
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==See Also==
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*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_22582791}}, adds the Publication Abstract to the page
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[[Category: Aliivibrio fischeri ES114]]
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(as it appears on PubMed at http://www.pubmed.gov), where 22582791 is the PubMed ID number.
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[[Category: Aliivibrio fischeri MJ11]]
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_22582791}}
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[[Category: Buts L]]
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[[Category: De Greve H]]
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==About this Structure==
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[[Category: De Jonge N]]
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[[4elz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aliivibrio_fischeri Aliivibrio fischeri]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3kua 3kua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELZ OCA].
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[[Category: Garcia-Pino A]]
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[[Category: Haesaerts S]]
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==Reference==
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[[Category: Lah J]]
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<ref group="xtra">PMID:022582791</ref><references group="xtra"/>
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[[Category: Loris R]]
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[[Category: Aliivibrio fischeri]]
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[[Category: Roelants K]]
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[[Category: Buts, L.]]
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[[Category: Simic M]]
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[[Category: Garcia-Pino, A.]]
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[[Category: Sterckx Y]]
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[[Category: Greve, H De.]]
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[[Category: Haesaerts, S.]]
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[[Category: Jonge, N De.]]
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[[Category: Lah, J.]]
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[[Category: Loris, R.]]
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[[Category: Roelants, K.]]
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[[Category: Simic, M.]]
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[[Category: Sterckx, Y.]]
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[[Category: Alpha+beta]]
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[[Category: Topoisomerase]]
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[[Category: Toxin-isomerase complex]]
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Current revision

CCDBVFI:GYRA14VFI

PDB ID 4elz

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