3egt

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[[Image:3egt.png|left|200px]]
 
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==T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722==
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The line below this paragraph, containing "STRUCTURE_3egt", creates the "Structure Box" on the page.
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<StructureSection load='3egt' size='340' side='right'caption='[[3egt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3egt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EGT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=722:1-(2,2-DIPHOSPHONOETHYL)-3-(HEPTYLOXY)PYRIDINIUM'>722</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3egt| PDB=3egt | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3egt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3egt OCA], [https://pdbe.org/3egt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3egt RCSB], [https://www.ebi.ac.uk/pdbsum/3egt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3egt ProSAT]</span></td></tr>
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</table>
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===T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722===
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== Function ==
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[https://www.uniprot.org/uniprot/Q86C09_9TRYP Q86C09_9TRYP]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 19309137 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eg/3egt_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_19309137}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[3egt]] is a 2 chain structure of [[Farnesyl diphosphate synthase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EGT OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3egt ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Farnesyl diphosphate synthase|Farnesyl diphosphate synthase]]
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019309137</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Geranyltranstransferase]]
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[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Cao, R.]]
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[[Category: Cao R]]
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[[Category: Gao, Y.]]
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[[Category: Gao Y]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Robinson, H.]]
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[[Category: Robinson H]]
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[[Category: Isoprene biosynthesis]]
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[[Category: Protein-bisphosphonate complex]]
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[[Category: Transferase]]
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Current revision

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722

PDB ID 3egt

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