2r8q

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[[Image:2r8q.png|left|200px]]
 
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==Structure of LmjPDEB1 in complex with IBMX==
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The line below this paragraph, containing "STRUCTURE_2r8q", creates the "Structure Box" on the page.
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<StructureSection load='2r8q' size='340' side='right'caption='[[2r8q]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2r8q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R8Q FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IBM:3-ISOBUTYL-1-METHYLXANTHINE'>IBM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_2r8q| PDB=2r8q | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r8q OCA], [https://pdbe.org/2r8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r8q RCSB], [https://www.ebi.ac.uk/pdbsum/2r8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r8q ProSAT]</span></td></tr>
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</table>
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===Structure of LmjPDEB1 in complex with IBMX===
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== Function ==
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[https://www.uniprot.org/uniprot/Q6S996_LEIMA Q6S996_LEIMA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17944832 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r8q_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17944832}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[2r8q]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R8Q OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r8q ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phosphodiesterase|Phosphodiesterase]]
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*[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:017944832</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
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[[Category: Leishmania major]]
[[Category: Leishmania major]]
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[[Category: Geng, J.]]
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[[Category: Geng J]]
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[[Category: Ke, H.]]
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[[Category: Ke H]]
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[[Category: Kunz, S.]]
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[[Category: Kunz S]]
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[[Category: Seebeck, T.]]
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[[Category: Seebeck T]]
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[[Category: Wang, H.]]
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[[Category: Wang H]]
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[[Category: Yan, Z.]]
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[[Category: Yan Z]]
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[[Category: Camp phosphodiesterase]]
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[[Category: Hydrolase]]
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[[Category: Leishimaniasis]]
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[[Category: Parasite inhibitor selectivity]]
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Current revision

Structure of LmjPDEB1 in complex with IBMX

PDB ID 2r8q

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