1xo7

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[[Image:1xo7.png|left|200px]]
 
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==Crystal structure of cyclophilin from Trypanosoma cruzi==
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The line below this paragraph, containing "STRUCTURE_1xo7", creates the "Structure Box" on the page.
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<StructureSection load='1xo7' size='340' side='right'caption='[[1xo7]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xo7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XO7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xo7 OCA], [https://pdbe.org/1xo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xo7 RCSB], [https://www.ebi.ac.uk/pdbsum/1xo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xo7 ProSAT]</span></td></tr>
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{{STRUCTURE_1xo7| PDB=1xo7 | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of cyclophilin from Trypanosoma cruzi===
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[https://www.uniprot.org/uniprot/Q4DPB9_TRYCC Q4DPB9_TRYCC] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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[[1xo7]] is a 4 chain structure of [[Cyclophilin]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XO7 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xo/1xo7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xo7 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cyclophilin|Cyclophilin]]
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Caruthers, J M.]]
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[[Category: Caruthers JM]]
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[[Category: Hol, W G.J.]]
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[[Category: Hol WGJ]]
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[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
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[[Category: Cis-tran]]
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[[Category: Cruzi]]
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[[Category: Cyclophilin]]
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[[Category: Isomerase]]
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[[Category: Proline]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Rotamase]]
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[[Category: Sgpp]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics of pathogenic protozoa consortium]]
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[[Category: Trypanosoma]]
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Current revision

Crystal structure of cyclophilin from Trypanosoma cruzi

PDB ID 1xo7

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