1qds

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[[Image:1qds.png|left|200px]]
 
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==SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM)==
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The line below this paragraph, containing "STRUCTURE_1qds", creates the "Structure Box" on the page.
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<StructureSection load='1qds' size='340' side='right'caption='[[1qds]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qds]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QDS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QDS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene></td></tr>
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{{STRUCTURE_1qds| PDB=1qds | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qds FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qds OCA], [https://pdbe.org/1qds PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qds RCSB], [https://www.ebi.ac.uk/pdbsum/1qds PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qds ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPIS_LEIME TPIS_LEIME]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/1qds_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qds ConSurf].
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<div style="clear:both"></div>
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===SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM)===
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==See Also==
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*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10785370}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10785370 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10785370}}
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==About this Structure==
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[[1qds]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QDS OCA].
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==Reference==
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<ref group="xtra">PMID:010785370</ref><references group="xtra"/>
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[[Category: Leishmania mexicana]]
[[Category: Leishmania mexicana]]
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[[Category: Triose-phosphate isomerase]]
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[[Category: Backmann J]]
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[[Category: Backmann, J.]]
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[[Category: Filimonov V]]
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[[Category: Filimonov, V.]]
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[[Category: Kursula I]]
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[[Category: Kursula, I.]]
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[[Category: Lambeir AM]]
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[[Category: Lambeir, A M.]]
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[[Category: Nielsen JE]]
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[[Category: Nielsen, J E.]]
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[[Category: Norledge BV]]
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[[Category: Norledge, B V.]]
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[[Category: Ruiz-Sanz J]]
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[[Category: Ruiz-Sanz, J.]]
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[[Category: Vriend G]]
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[[Category: Vriend, G.]]
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[[Category: Wierenga RK]]
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[[Category: Wierenga, R K.]]
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[[Category: Isomerase]]
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[[Category: Leishmania]]
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[[Category: Mutagenesis]]
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[[Category: Pka]]
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[[Category: Stability]]
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[[Category: Tim]]
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Current revision

SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM)

PDB ID 1qds

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OCA

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