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1p19

From Proteopedia

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_1p19", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:1p19.png|left|200px]]
 
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==Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, in complex with the product IMP==
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The line below this paragraph, containing "STRUCTURE_1p19", creates the "Structure Box" on the page.
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<StructureSection load='1p19' size='340' side='right'caption='[[1p19]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p19]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P19 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
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{{STRUCTURE_1p19| PDB=1p19 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p19 OCA], [https://pdbe.org/1p19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p19 RCSB], [https://www.ebi.ac.uk/pdbsum/1p19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p19 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4DRC4_TRYCC Q4DRC4_TRYCC]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p1/1p19_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p19 ConSurf].
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<div style="clear:both"></div>
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===Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, in complex with the product IMP===
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 14698288 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14698288}}
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==About this Structure==
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[[1p19]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P19 OCA].
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==Reference==
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<ref group="xtra">PMID:014698288</ref><references group="xtra"/>
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[[Category: Hypoxanthine phosphoribosyltransferase]]
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[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
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[[Category: Eakin, A E.]]
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[[Category: Craig III SP]]
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[[Category: III, S P.Craig.]]
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[[Category: Eakin AE]]
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[[Category: Medrano, F J.]]
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[[Category: Medrano FJ]]
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[[Category: Glycosyltransferase]]
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[[Category: Nucleotide metabolism]]
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[[Category: Phosphoribosyltransferase]]
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[[Category: Product complex]]
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[[Category: Purine salvage]]
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[[Category: Transferase]]
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Current revision

Hypoxanthine Phosphoribosyltransferase from Trypanosoma cruzi, in complex with the product IMP

PDB ID 1p19

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OCA

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