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3bwc

From Proteopedia

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_3bwc", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:3bwc.png|left|200px]]
 
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==Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A resolution==
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The line below this paragraph, containing "STRUCTURE_3bwc", creates the "Structure Box" on the page.
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<StructureSection load='3bwc' size='340' side='right'caption='[[3bwc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3bwc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BWC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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{{STRUCTURE_3bwc| PDB=3bwc | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bwc OCA], [https://pdbe.org/3bwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bwc RCSB], [https://www.ebi.ac.uk/pdbsum/3bwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bwc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4DA73_TRYCC Q4DA73_TRYCC]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/3bwc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bwc ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A resolution===
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==See Also==
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*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3bwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BWC OCA].
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[[Category: Large Structures]]
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[[Category: Spermidine synthase]]
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[[Category: Trypanosoma cruzi strain CL Brener]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Arakaki TL]]
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[[Category: Arakaki, T L.]]
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[[Category: Bosch J]]
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[[Category: Bosch, J.]]
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[[Category: Hol WGJ]]
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[[Category: Hol, W G.J.]]
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[[Category: Le Trong I]]
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[[Category: Merritt, E A.]]
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[[Category: Merritt EA]]
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[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
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[[Category: Trong, I Le.]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Sam]]
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[[Category: Sgpp]]
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[[Category: Spermidine synthase]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics of pathogenic protozoa consortium]]
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[[Category: Transferase]]
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[[Category: Trypanosoma cruzi]]
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Current revision

Crystal structure of spermidine synthase from Trypanosoma cruzi in complex with SAM at 2.3 A resolution

PDB ID 3bwc

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