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1mz6

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_1mz6", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:1mz6.png|left|200px]]
 
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==Trypanosoma rangeli sialidase in complex with the inhibitor DANA==
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The line below this paragraph, containing "STRUCTURE_1mz6", creates the "Structure Box" on the page.
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<StructureSection load='1mz6' size='340' side='right'caption='[[1mz6]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_rangeli Trypanosoma rangeli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MZ6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC+ACID'>DAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1mz6| PDB=1mz6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mz6 OCA], [https://pdbe.org/1mz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mz6 RCSB], [https://www.ebi.ac.uk/pdbsum/1mz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mz6 ProSAT]</span></td></tr>
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</table>
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===Trypanosoma rangeli sialidase in complex with the inhibitor DANA===
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== Function ==
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[https://www.uniprot.org/uniprot/O44049_TRYRA O44049_TRYRA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10619840 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mz/1mz6_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10619840}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1mz6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_rangeli Trypanosoma rangeli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZ6 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mz6 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:010619840</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Exo-alpha-sialidase]]
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[[Category: Large Structures]]
[[Category: Trypanosoma rangeli]]
[[Category: Trypanosoma rangeli]]
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[[Category: Alzari, P M.]]
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[[Category: Alzari PM]]
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[[Category: Amaya, M F.]]
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[[Category: Amaya MF]]
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[[Category: Buschiazzo, A.]]
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[[Category: Buschiazzo A]]
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[[Category: Campetella, O.]]
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[[Category: Campetella O]]
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[[Category: Cremona, M L.]]
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[[Category: Cremona ML]]
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[[Category: Frasch, A C.C.]]
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[[Category: Frasch ACC]]
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[[Category: Paris, G.]]
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[[Category: Paris G]]
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[[Category: Spinelli, S.]]
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[[Category: Spinelli S]]
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[[Category: Tavares, G A.]]
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[[Category: Tavares GA]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Inibitor complex]]
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[[Category: Sialyltransferase]]
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[[Category: Trypanosomal sialidase]]
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Current revision

Trypanosoma rangeli sialidase in complex with the inhibitor DANA

PDB ID 1mz6

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