2b56

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2b56" [edit=sysop:move=sysop])
Current revision (09:16, 14 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2b56.png|left|200px]]
 
-
<!--
+
==Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei==
-
The line below this paragraph, containing "STRUCTURE_2b56", creates the "Structure Box" on the page.
+
<StructureSection load='2b56' size='340' side='right'caption='[[2b56]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2b56]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B56 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B56 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U5P:URIDINE-5-MONOPHOSPHATE'>U5P</scene>, <scene name='pdbligand=UTP:URIDINE+5-TRIPHOSPHATE'>UTP</scene></td></tr>
-
{{STRUCTURE_2b56| PDB=2b56 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b56 OCA], [https://pdbe.org/2b56 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b56 RCSB], [https://www.ebi.ac.uk/pdbsum/2b56 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b56 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/TUT2_TRYBB TUT2_TRYBB] Terminal uridylyltransferase which, as part of the mitochondrial RNA editing core complex (RECC), is involved in the post-transcriptional editing of mitochondrial RNA, a process involving the addition and deletion of uridine (U) nucleotides in the pre-mRNA (PubMed:12820966, PubMed:19465686, PubMed:20362585). Specifically, catalyzes the addition of one U to single-stranded RNA with a preference for a 3'-terminal A or G and adds the number of Us specified by a guide RNA (gRNA) to precleaved double-stranded RNA editing substrates (PubMed:12820966, PubMed:19465686, PubMed:20362585, PubMed:16281058). Essential for the survival of the bloodstream form (PubMed:16281058).<ref>PMID:12820966</ref> <ref>PMID:16281058</ref> <ref>PMID:19465686</ref> <ref>PMID:20362585</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_16281058}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 16281058 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b56_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_16281058}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
[[2b56]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B56 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b56 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:016281058</ref><ref group="xtra">PMID:017785418</ref><references group="xtra"/>
+
<references/>
-
[[Category: Trypanosoma brucei]]
+
__TOC__
-
[[Category: Deng, J.]]
+
</StructureSection>
-
[[Category: Ernst, N L.]]
+
[[Category: Large Structures]]
-
[[Category: Hol, W G.]]
+
-
[[Category: Stuart, K D.]]
+
-
[[Category: Turley, S.]]
+
-
[[Category: Rna editing]]
+
-
[[Category: Tbret2]]
+
-
[[Category: Transferase]]
+
-
[[Category: Transferase-rna binding protein complex]]
+
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
-
[[Category: Tutase]]
+
[[Category: Deng J]]
 +
[[Category: Ernst NL]]
 +
[[Category: Hol WG]]
 +
[[Category: Stuart KD]]
 +
[[Category: Turley S]]

Current revision

Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei

PDB ID 2b56

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2b56"
Personal tools