3bje

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[[Image:3bje.png|left|200px]]
 
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==Crystal structure of Trypanosoma brucei nucleoside phosphorylase shows uridine phosphorylase activity==
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The line below this paragraph, containing "STRUCTURE_3bje", creates the "Structure Box" on the page.
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<StructureSection load='3bje' size='340' side='right'caption='[[3bje]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3bje]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BJE FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.44&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
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{{STRUCTURE_3bje| PDB=3bje | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bje OCA], [https://pdbe.org/3bje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bje RCSB], [https://www.ebi.ac.uk/pdbsum/3bje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bje ProSAT]</span></td></tr>
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</table>
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===Crystal structure of Trypanosoma brucei nucleoside phosphorylase shows uridine phosphorylase activity===
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== Function ==
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[https://www.uniprot.org/uniprot/Q57VZ2_TRYB2 Q57VZ2_TRYB2]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 20070944 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/3bje_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_20070944}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[3bje]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJE OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bje ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:020070944</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
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[[Category: Larson, E T.]]
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[[Category: Larson ET]]
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[[Category: Merritt, E A.]]
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[[Category: Merritt EA]]
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[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]]
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[[Category: Brucei]]
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[[Category: Glycosyltransferase]]
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[[Category: Medical structural genomics of pathogenic protozoa consortium]]
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[[Category: Msgpp]]
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[[Category: Nucleoside phosphorylase]]
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[[Category: Sleeping sickness]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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[[Category: Trypanosoma]]
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[[Category: Uridine phosphorylase]]
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Current revision

Crystal structure of Trypanosoma brucei nucleoside phosphorylase shows uridine phosphorylase activity

PDB ID 3bje

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