1ezr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_1ezr", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
Current revision (07:09, 7 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ezr.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR==
-
The line below this paragraph, containing "STRUCTURE_1ezr", creates the "Structure Box" on the page.
+
<StructureSection load='1ezr' size='340' side='right'caption='[[1ezr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ezr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EZR FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
{{STRUCTURE_1ezr| PDB=1ezr | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ezr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezr OCA], [https://pdbe.org/1ezr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ezr RCSB], [https://www.ebi.ac.uk/pdbsum/1ezr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezr ProSAT]</span></td></tr>
-
 
+
</table>
-
===CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/IUNH_LEIMA IUNH_LEIMA] Catalyzes the hydrolysis of all of the commonly occurring purine and pyrimidine nucleosides into ribose and the associated base, but has a preference for inosine and uridine as substrates.<ref>PMID:10409664</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_10409664}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 10409664 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ez/1ezr_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_10409664}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
[[1ezr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZR OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ezr ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:010409664</ref><references group="xtra"/>
+
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Leishmania major]]
[[Category: Leishmania major]]
-
[[Category: Purine nucleosidase]]
+
[[Category: Almo SC]]
-
[[Category: Almo, S C.]]
+
[[Category: Schramm VL]]
-
[[Category: Schramm, V L.]]
+
[[Category: Shi W]]
-
[[Category: Shi, W.]]
+
-
[[Category: Alpha/beta fold]]
+
-
[[Category: Hydrolase]]
+

Current revision

CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR

PDB ID 1ezr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools