This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3iy8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3iy8" [edit=sysop:move=sysop])
Current revision (10:07, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3iy8.png|left|200px]]
 
-
<!--
+
==Leishmania tarentolae Mitonchondrial Ribosome small subunit==
-
The line below this paragraph, containing "STRUCTURE_3iy8", creates the "Structure Box" on the page.
+
<SX load='3iy8' size='340' side='right' viewer='molstar' caption='[[3iy8]], [[Resolution|resolution]] 14.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3iy8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IY8 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14.1&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iy8 OCA], [https://pdbe.org/3iy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iy8 RCSB], [https://www.ebi.ac.uk/pdbsum/3iy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iy8 ProSAT]</span></td></tr>
-
{{STRUCTURE_3iy8| PDB=3iy8 | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Leishmania tarentolae Mitonchondrial Ribosome small subunit===
+
[https://www.uniprot.org/uniprot/RS5_ECOLI RS5_ECOLI] With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).<ref>PMID:15652481</ref> Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<ref>PMID:15652481</ref> The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp.<ref>PMID:15652481</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_19497863}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 19497863 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iy8_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_19497863}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iy8 ConSurf].
-
[[3iy8]] is a 11 chain structure of [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S15]], [[Ribosomal protein S16]], [[Ribosomal protein S17]], [[Ribosomal protein S18]], [[Ribosomal protein S5]], [[Ribosomal protein S6]], [[Ribosomal protein S8]] and [[Ribosomal protein S9]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA].
+
<div style="clear:both"></div>
==See Also==
==See Also==
Line 28: Line 27:
*[[Ribosomal protein S17|Ribosomal protein S17]]
*[[Ribosomal protein S17|Ribosomal protein S17]]
*[[Ribosomal protein S18|Ribosomal protein S18]]
*[[Ribosomal protein S18|Ribosomal protein S18]]
-
*[[Ribosomal protein S5|Ribosomal protein S5]]
 
-
*[[Ribosomal protein S6|Ribosomal protein S6]]
 
*[[Ribosomal protein S8|Ribosomal protein S8]]
*[[Ribosomal protein S8|Ribosomal protein S8]]
*[[Ribosomal protein S9|Ribosomal protein S9]]
*[[Ribosomal protein S9|Ribosomal protein S9]]
-
 
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:019497863</ref><references group="xtra"/>
+
<references/>
-
[[Category: Escherichia coli]]
+
__TOC__
-
[[Category: Leishmania tarentolae]]
+
</SX>
-
[[Category: Agrawal, R K.]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Booth, T M.]]
+
[[Category: Large Structures]]
-
[[Category: Maslov, D A.]]
+
-
[[Category: Sharma, M R.]]
+
-
[[Category: Simpson, L.]]
+
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Cryoem]]
+
-
[[Category: Endonuclease]]
+
-
[[Category: Hydrolase]]
+
[[Category: Leishmania tarentolae]]
[[Category: Leishmania tarentolae]]
-
[[Category: Methylation]]
+
[[Category: Agrawal RK]]
-
[[Category: Minimal rna.]]
+
[[Category: Booth TM]]
-
[[Category: Mitochondrial ribosome]]
+
[[Category: Maslov DA]]
-
[[Category: Nuclease]]
+
[[Category: Sharma MR]]
-
[[Category: Repressor]]
+
[[Category: Simpson L]]
-
[[Category: Ribonucleoprotein]]
+
-
[[Category: Ribosomal protein]]
+
-
[[Category: Ribosome]]
+
-
[[Category: Rna-binding]]
+
-
[[Category: Rrna-binding]]
+
-
[[Category: Translation regulation]]
+
-
[[Category: Trna-binding]]
+

Current revision

Leishmania tarentolae Mitonchondrial Ribosome small subunit

3iy8, resolution 14.10Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools