3qrf

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[[Image:3qrf.png|left|200px]]
 
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==Structure of a domain-swapped FOXP3 dimer==
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<StructureSection load='3qrf' size='340' side='right'caption='[[3qrf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qrf]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3qrf| PDB=3qrf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrf OCA], [https://pdbe.org/3qrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrf RCSB], [https://www.ebi.ac.uk/pdbsum/3qrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrf ProSAT]</span></td></tr>
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</table>
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===Structure of a domain-swapped FOXP3 dimer===
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== Function ==
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[https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref>
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(as it appears on PubMed at http://www.pubmed.gov), where 21458306 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21458306}}
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==About this Structure==
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[[3qrf]] is a 10 chain structure of [[Forkhead box protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRF OCA].
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==See Also==
==See Also==
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*[[Forkhead Box Protein 3|Forkhead Box Protein 3]]
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*[[FOX 3D structures|FOX 3D structures]]
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*[[Forkhead box protein|Forkhead box protein]]
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:021458306</ref><references group="xtra"/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bandukwala, H S.]]
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[[Category: Large Structures]]
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[[Category: Barbosa, B]]
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[[Category: Bandukwala HS]]
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[[Category: Benoist, C.]]
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[[Category: Barbosa B]]
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[[Category: Chen, L.]]
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[[Category: Benoist C]]
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[[Category: Chen, Y]]
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[[Category: Chen L]]
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[[Category: Feurer, M]]
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[[Category: Chen Y]]
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[[Category: Ghosh, S]]
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[[Category: Feurer M]]
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[[Category: Mathis, D.]]
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[[Category: Ghosh S]]
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[[Category: Rao, A.]]
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[[Category: Mathis D]]
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[[Category: Stroud, J C.]]
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[[Category: Rao A]]
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[[Category: Wu, Y]]
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[[Category: Stroud JC]]
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[[Category: Beta barrel]]
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[[Category: Wu Y]]
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[[Category: Dna binding]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Domain swap]]
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[[Category: Double helix]]
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[[Category: Forkhead domain]]
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[[Category: Immnoglobulin fold]]
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[[Category: Nucleus]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription regulation]]
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Current revision

Structure of a domain-swapped FOXP3 dimer

PDB ID 3qrf

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