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1d66

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_1d66", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:1d66.png|left|200px]]
 
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==DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX==
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The line below this paragraph, containing "STRUCTURE_1d66", creates the "Structure Box" on the page.
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<StructureSection load='1d66' size='340' side='right'caption='[[1d66]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1d66]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D66 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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{{STRUCTURE_1d66| PDB=1d66 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d66 OCA], [https://pdbe.org/1d66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d66 RCSB], [https://www.ebi.ac.uk/pdbsum/1d66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d66 ProSAT]</span></td></tr>
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</table>
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===DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX===
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== Function ==
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[https://www.uniprot.org/uniprot/GAL4_YEAST GAL4_YEAST] This protein is a positive regulator for the gene expression of the galactose-induced genes such as GAL1, GAL2, GAL7, GAL10, and MEL1 which code for the enzymes used to convert galactose to glucose. It recognizes a 17 base pair sequence in (5'-CGGRNNRCYNYNCNCCG-3') the upstream activating sequence (UAS-G) of these genes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 1557122 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d6/1d66_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_1557122}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1d66]] is a 4 chain structure of [[Gal4]] and [[Hydrogen in macromolecular models]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D66 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d66 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Gal4|Gal4]]
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*[[Gal3-Gal80-Gal4|Gal3-Gal80-Gal4]]
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*[[Gal4 (Hebrew)|Gal4 (Hebrew)]]
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*[[Getting Unremediated PDB Files|Getting Unremediated PDB Files]]
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*[[Hydrogen in macromolecular models|Hydrogen in macromolecular models]]
*[[Hydrogen in macromolecular models|Hydrogen in macromolecular models]]
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*[[Jmol/Application|Jmol/Application]]
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__TOC__
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*[[Molecular Playground/Procedures|Molecular Playground/Procedures]]
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</StructureSection>
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*[[User:Amir Mitchell/hebrew Gal4|User:Amir Mitchell/hebrew Gal4]]
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[[Category: Large Structures]]
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*[[User:Amir Mitchell/hebrew IPNS|User:Amir Mitchell/hebrew IPNS]]
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*[[User:Wayne Decatur/Biochem642 Molecular Visualization 2010 Fall Sessions|User:Wayne Decatur/Biochem642 Molecular Visualization 2010 Fall Sessions]]
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*[[User:Wayne Decatur/Biochem642 Molecular Visualization Sessions|User:Wayne Decatur/Biochem642 Molecular Visualization Sessions]]
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==Reference==
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<ref group="xtra">PMID:001557122</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Carey, M.]]
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[[Category: Carey M]]
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[[Category: Harrison, S C.]]
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[[Category: Harrison SC]]
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[[Category: Marmorstein, R.]]
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[[Category: Marmorstein R]]
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[[Category: Ptashne, M.]]
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[[Category: Ptashne M]]
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[[Category: Double helix]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription-dna complex]]
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Current revision

DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX

PDB ID 1d66

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