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1mb1

From Proteopedia

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(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_1mb1", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
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[[Image:1mb1.png|left|200px]]
 
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==MBP1 FROM SACCHAROMYCES CEREVISIAE==
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The line below this paragraph, containing "STRUCTURE_1mb1", creates the "Structure Box" on the page.
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<StructureSection load='1mb1' size='340' side='right'caption='[[1mb1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mb1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MB1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MB1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mb1 OCA], [https://pdbe.org/1mb1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mb1 RCSB], [https://www.ebi.ac.uk/pdbsum/1mb1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mb1 ProSAT]</span></td></tr>
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{{STRUCTURE_1mb1| PDB=1mb1 | SCENE= }}
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</table>
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== Function ==
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===MBP1 FROM SACCHAROMYCES CEREVISIAE===
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[https://www.uniprot.org/uniprot/MBP1_YEAST MBP1_YEAST] Binds to MCB elements (Mlu I cell cycle box) found in the promoter of most DNA synthesis genes. Transcriptional activation by MBF has an important role in the transition from G1 to S phase. It may have a dual role in that it behaves as an activator of transcription at the G1-S boundary and as a repressor during other stages of the cell cycle.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 9299332 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mb1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_9299332}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mb1 ConSurf].
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[[1mb1]] is a 1 chain structure of [[MBP1]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MB1 OCA].
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<div style="clear:both"></div>
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__TOC__
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==See Also==
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</StructureSection>
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*[[MBP1|MBP1]]
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:009299332</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Smerdon, S J.]]
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[[Category: Smerdon SJ]]
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[[Category: Taylor, I A.]]
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[[Category: Taylor IA]]
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[[Category: Cell-cycle]]
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[[Category: Transcription factor]]
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[[Category: Transcription regulation]]
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Current revision

MBP1 FROM SACCHAROMYCES CEREVISIAE

PDB ID 1mb1

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