1q45

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[[Image:1q45.png|left|200px]]
 
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==12-0xo-phytodienoate reductase isoform 3==
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The line below this paragraph, containing "STRUCTURE_1q45", creates the "Structure Box" on the page.
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<StructureSection load='1q45' size='340' side='right'caption='[[1q45]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q45]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q45 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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{{STRUCTURE_1q45| PDB=1q45 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q45 OCA], [https://pdbe.org/1q45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q45 RCSB], [https://www.ebi.ac.uk/pdbsum/1q45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q45 ProSAT], [https://www.topsan.org/Proteins/CESG/1q45 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/OPR3_ARATH OPR3_ARATH] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. Required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program. In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively. Can detoxify the explosive 2,4,6-trinitrotoluene (TNT) in vitro by catalyzing its nitroreduction to form hydroxylamino-dinitrotoluene (HADNT).<ref>PMID:10973494</ref> <ref>PMID:19605548</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q4/1q45_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q45 ConSurf].
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<div style="clear:both"></div>
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===12-0xo-phytodienoate reductase isoform 3===
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==See Also==
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*[[12-oxophytodienoate reductase 3D structures|12-oxophytodienoate reductase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[1q45]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q45 OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015468319</ref><ref group="xtra">PMID:016080145</ref><references group="xtra"/>
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[[Category: 12-oxophytodienoate reductase]]
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Bingman, C A.]]
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[[Category: Large Structures]]
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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[[Category: Bingman CA]]
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[[Category: Johnson, K A.]]
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[[Category: Johnson KA]]
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[[Category: Phillips, G N.]]
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[[Category: Phillips Jr GN]]
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[[Category: Smith, D W.]]
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[[Category: Smith DW]]
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[[Category: Center for eukaryotic structural genomic]]
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[[Category: Cesg]]
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[[Category: Flavoenzyme]]
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[[Category: Flavoprotein]]
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[[Category: Old yellow enzyme]]
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[[Category: Oxidoreductase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Secondary messenger]]
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[[Category: Structural genomic]]
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[[Category: Xenobiotic reductase]]
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Current revision

12-0xo-phytodienoate reductase isoform 3

PDB ID 1q45

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OCA

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