1xbw

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[[Image:1xbw.png|left|200px]]
 
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==1.9A Crystal Structure of the protein isdG from Staphylococcus aureus aureus, Structural genomics, MCSG==
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The line below this paragraph, containing "STRUCTURE_1xbw", creates the "Structure Box" on the page.
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<StructureSection load='1xbw' size='340' side='right'caption='[[1xbw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xbw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MW2 Staphylococcus aureus subsp. aureus MW2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XBW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbw OCA], [https://pdbe.org/1xbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xbw RCSB], [https://www.ebi.ac.uk/pdbsum/1xbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xbw ProSAT], [https://www.topsan.org/Proteins/MCSG/1xbw TOPSAN]</span></td></tr>
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{{STRUCTURE_1xbw| PDB=1xbw | SCENE= }}
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</table>
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== Function ==
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===1.9A Crystal Structure of the protein isdG from Staphylococcus aureus aureus, Structural genomics, MCSG===
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[https://www.uniprot.org/uniprot/HDOX1_STAAW HDOX1_STAAW] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_15520015}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15520015 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xb/1xbw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15520015}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xbw ConSurf].
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[[1xbw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus Staphylococcus aureus subsp. aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBW OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015520015</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus]]
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[[Category: Staphylococcus aureus subsp. aureus MW2]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, G.]]
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[[Category: Joachimiak G]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Schneewind O]]
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[[Category: Schneewind, O.]]
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[[Category: Wu R]]
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[[Category: Wu, R.]]
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[[Category: Zhang R]]
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[[Category: Zhang, R.]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein isdg]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Staphylococcus aureus]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

1.9A Crystal Structure of the protein isdG from Staphylococcus aureus aureus, Structural genomics, MCSG

PDB ID 1xbw

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