3gv2

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[[Image:3gv2.png|left|200px]]
 
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==X-ray Structure of Hexameric HIV-1 CA==
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The line below this paragraph, containing "STRUCTURE_3gv2", creates the "Structure Box" on the page.
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<StructureSection load='3gv2' size='340' side='right'caption='[[3gv2]], [[Resolution|resolution]] 7.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3gv2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(NEW_YORK-5_ISOLATE) Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)] and [https://en.wikipedia.org/wiki/Synechocystis_sp._PCC_6803_substr._Kazusa Synechocystis sp. PCC 6803 substr. Kazusa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GV2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gv2 OCA], [https://pdbe.org/3gv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gv2 RCSB], [https://www.ebi.ac.uk/pdbsum/3gv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gv2 ProSAT]</span></td></tr>
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{{STRUCTURE_3gv2| PDB=3gv2 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GAG_HV1N5 GAG_HV1N5] Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu. Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers. p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity).[https://www.uniprot.org/uniprot/CCMK4_SYNY3 CCMK4_SYNY3] May be involved in the formation of the carboxysome, a polyhedral inclusion where RuBisCO is sequestered (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/3gv2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gv2 ConSurf].
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<div style="clear:both"></div>
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===X-ray Structure of Hexameric HIV-1 CA===
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==See Also==
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*[[Virus coat protein|Virus coat protein]]
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 19523676 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Synechocystis sp. PCC 6803 substr. Kazusa]]
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{{ABSTRACT_PUBMED_19523676}}
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[[Category: Kelly BN]]
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==About this Structure==
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[[3gv2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(new_york-5_isolate),_synechocystis_sp. Human immunodeficiency virus type 1 (new york-5 isolate), synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GV2 OCA].
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==Reference==
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<ref group="xtra">PMID:019523676</ref><references group="xtra"/>
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[[Category: Kelly, B N.]]
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[[Category: Hexameric retroviral capsid]]
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[[Category: Viral protein]]
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Current revision

X-ray Structure of Hexameric HIV-1 CA

PDB ID 3gv2

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Proteopedia Page Contributors and Editors (what is this?)

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